Publications - 2013

Yerko, V., Sulea, T., Ekiel, I., Harcus, D., Baardsnes, J., Cygler, M., Whiteway, M., and Wu, C. (2013). Structurally unique interaction of RBD-like and PH domains is crucial for yeast pheromone signaling. Mol. Biol. Cell, 24, 409-20.

Grishin, A.M., Ajamian, E., Tao, L.-M., Bostina, M., Zhang, L., Trempe, J.-F., Menard, R., Rouiller, I. and Cygler, M. (2013). Spatial Organization of Subunits within the Phenylacetyl-Coa Monooxygenase Complex. J. Struct. Biol., 184, 147-154.

Cygler, M. and Petkun, S. (2013). Hydrogenase maturation protein HypF. In Encyclopedia of Inorganic and Bioinorganic Chemistry, ed R.A. Scott, section editor A. Messerschmidt, John Wiley:Chichester. Published 9/23/2013. DOI: 10.1002/9781119951438.eibc2167.

Grishin, A.M., Cherney, M., Anderson, D.H., Phanse, S., Babu, M. and Cygler, M. (2013). NleH Defines a New Family of Bacterial Effector Kinases. Structure, 22, 250-259.

Shi, R., McDonald, L., Cygler, M. and Ekiel, I. (2013). Coiled-coil Helix Rotation Selects between Repressing and Activating State of Transcriptional Regulator DhaR. Structure, 22, 478-487.

Kalynych, S., Morona R. and Cygler M. (2013). Progress in Understanding the Assembly Process of Bacterial O-Antigen. FEMS Microbiology Review, Mar 11. doi: 10.1111/1574-6976.12070.

Du, L., Luo, Y. (2013) Structure of a filament of stacked octamers of human DMC1 recombinase. Acta Cryst. F, 69, 382-6.

Desin, T.S., Köster, W., and Potter, A.A. (2013) Salmonella vaccines:  past, present and future. Expert Review of Vaccines. 12(1), 87-96.

Mertins, S., Allan, B., Townsend, H., Köster, W., and Potter, A.A. (2013) Role of motAB in adherence and internalization in polarized Caco-2 cells and in cecal colonization of Campylobacter jejuni. Avian Diseases 57(1), 116-22.

Basquin, C., Malardé, V., Mellor, P., Anderson, D.H., Meas-Yedid, V., Olivo-Martin, J.-C., Dautry-Varsat, A., Sauvonnet, N. (2013) The signalling factor PI 3-kinase is a specific regulator of the clathrin-independent dynamin-dependent endocytosis of IL-2 receptors. J. Cell Sci., 126,1099-108.

Dalrymple, S.A., Ko, J.K., Sheoran, I.S., Kaminskyj, S.G.W., Sanders, D.A.R. (2013) Elucidation of substrate specificity in Aspergillus nidulans UDP-galactose-4-epimerase. PLoS One, in press.

Alam, M,K,, Kaminskyj, S.G.W. (2013) Aspergillus galactose metabolism is more complex than Saccharomyces: the story of GalDGAL7 and GalE GAL1. Botany 91, 467-477

Kharenko, O.A., Polichuk,D., Nelson, K.M., Abrams, S.R., Loewen, M.C. (2013) Identification and characterization of interactions between abscisic acid and human heat shock protein 70 family members.  J. Biochem. in pres.

Kharenko, O.A., Choudhary, P., Loewen, M.C., (2013) Abscisic Acid binds to Recombinant Arabidopsis G-protein Coupled Receptor Type-G-protein 1 in S. cerevisiae and in vitro.  Plant Physiol. and Biochem., 68, 32-36.

Dorosh, L., Kharenko, O., A., Rajagopalan, K., Loewen M.C., Stepanova, M.  (2013)  Molecular Mechanisms in the Selective Basal Activation of Pyrabactin Receptor 1: Evidence for Competing Complexes. PLoS Computational Biology, 9:e1003114: 1-17.

Loewen,P.C., Didychuk,A.L., Switala, J., Perez-Luque, R., Fita, I., Loewen, M.C. (2013) Structure of Pisum Sativum Rubisco with bound ribulose 1,5-bisphosphate Acta Cryst. F, 69, 10-14.

Adolph, M.B., Webb, J., Chelico, L. (2013) Retroviral Restriction Factor APOBEC3G Delays the Initiation of DNA Synthesis by HIV-1 Reverse Transcriptase. PLoS One 8(5), e64196.

Feng, Y, Love, R.P., Chelico, L. (2013) HIV-1 Viral infectivity factor (Vif) alters processive single-stranded DNA scanning of the retroviral restriction factor APOBEC3G. J. Biol. Chem., 288, 6083-6094.

Gorin, J., Blomqvist, I., Sigrist, M., Summers, T., Fodje, M. and Grochulski, P. (2013) "Measured performance of hybrid small-gap in-vacuum undulator 08ID-1 at the CLS intermediate energy storage ring". Journal of Physics: Conference Series, 425, 177

Martynowsk, D., Grochulski P., Howard P. (2013) Structure of a periplasmic domain of the EpsAB fusion proteinof the Vibrio vulnificus type II secretion system. Acta Cryst.  D69, 142–149

Gangola, M.P., Khedikar, Y.P., Gaur, P.M., Båga, M. and Chibbar, R.N. (2013) Genotype and growing environment interaction shows a positive correlation between substrates of raffinose family oligosaccharides (RFO) biosynthesis and accumulation in chickpea (Cicer arietinum L.) seeds. J. Agric. Food Chem. 61:4943 - 4952

Sharma, P., Ganeshan, S., Fowler, D.B. and Chibbar, R.N. (2013) characterization of two wheat enolase cDNA showing distinct patterns of expression in leaf and crown tissues of plants exposed to low temperature.  Annals of Applied Biology 162: 271-283.

Dolgova NV, Nokhrin S, Yu CH, George GN, Dmitriev OY. (2013) Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification. Biochem J. 454, 147-156.

Bharathikumar VM, Barreto K, Decoteau JF, Geyer CR. (2013). Allosteric Lariat Peptide Inhibitors of Abl Kinase. Chembiochem. doi: 10.1002/cbic.201300253.

Das U, Singh RSP, Alcorn J, Hickman MR, Sciotti RS, Leed SE, Lee, PJ, Roncal N, Dimmock JR (2013). 3,5-bis(Benzylidene)-4-piperidones and related N-acyl analogs: A novel cluster of antimalarials targeting the liver stage of Plasmodium falciparum. Bioorganic & Medicinal Chemistry 21(23):7250-6.

Lin C, Krol E, Alcorn J (2013). The comparison of rat and human intestinal and hepatic glucuronidation of enterolactone derived from flaxseed lignans. Natural Products Journal 13(3): 159-171.

Berry MD, Shitut MR, Al-Moussa A, Alcorn J, Tomberli B (2013). Membrane Permeability of Trace Amines: Evidence for a Regulated, Activity-dependent, Non-exocytotic, Synaptic Release. Synapse 67(10):656-67.

Billinsky J, Glew RA, Cornish SM, Chilibeck PD, Whiting SJ, Thorpe LU, Alcorn J, Paus-Jenssen L, Hadjistavropoulos T. (2013). No Evidence of Adverse Effect on Blood Glucose or Blood Pressure in Middle Aged or Older Adults Following 6 Months of Flax Lignan Supplementation in a Randomized Controlled Trial. Pharmaceut Biol 51(6):778-782.

Viveky N, Billinsky J, Thorpe LU, Alcorn J, Hadjistavropoulos T, Whiting S (2013). Continued challenges in meeting dietary recommendations in long-term care meals. (Accepted to Canadian Journal of Dietetic Practice and Research)

Sultan A, Ling BB, Zhang H, Ma B, Michel D, Alcorn J, Yang J. (2013) Synergistic effect between sphingosine-1-phosphate and chemotherapy drugs agains human brain-metastasized breast cancer MDA-MB-361 cells. J Cancer 4(4):315-319.

 Singh RSP, Das U, Auschwitz JM, Leed SE, Hickman MR, Dimmock JR, Alcorn J (2013). From a cytotoxic agent to the discovery of a novel antimalarial agent. Bioorganic and Medicinal Chemistry Letters 23:584-7.

Henderson, A., Wu, Y., Huang, Y., Chavez, L., Platt, J., Johnson, F.B., Brosh, R., Sen, D., and Lansdorp, P.M. (2013). Detection of G-quadruplex DNA in mammalian cells.  Nucleic Acids Res. In press. PMID: 24163102

Guo, M. and Wu, Y. (2013). Fighting an Old War with a New Weapon—Silencing Transposons by piRNA. IUBMB Life. In press (PMID: 23893818).

Trost, B., Kindrachuk, J., Maattanen, P., Napper, S. and Kusalik, A (2013) PIIKA2: An Expanded, Web-based Platform for Analysis of Kinome Microarray Data. Accepted by PLOSone Oct 27, 2013

Maattanen, P., Taschuk, R., Ross, L., Marciniuk, K., Bertram, L., Potter, A., Cashman, N. and Napper, S. (2013) PrPSc-specific antibodies do not induce prion disease or misfolding of PrPC in highly susceptible Tga20 mice. Prion. Oct 8;7(5) epub ahead of print

 Marciniuk, K., Taschuk, R. and Napper, S. (2013) Evidence for Prion-like Mechanisms in Several Neurodegenerative Diseases: Potential Implications for Immunotherapy. Clinical and Developmental Immunology

 Mulongo, M., Prysliak, T., Scruten, E., Napper, S. and Perez-Casal, J. (2013) In vitro infection of bovine monocytes with Mycoplasma bovis delays apoptosis and suppresses production of IFNg and TNFa but not Il-10. Infect. Immun. Oct 14 Epud ahead of print

Maattanen, P., Trost, B., Scuten, E., Potter, A., Kusalik, A., Griebel, P. and Napper, S. (2013) Divergent Immune Responses to Mycobacterium avium subsp. paratuberculosis Correlate with Kinome Responses at the Site of Intestinal Infection. Infect. Immun. Epud ahead of print May 28 Impact Factor 4.2

Madampage, C. A., Maattanen, P., Marciniuk, K., Brownlie, R., Andrievskaia, O., Potter, A., Cashman, N., Lee, J. S. and Napper, S. (2013) Binding of bovine T194A PrPC by PrPSc-specific antibodies: Potential implications for immunotherapy of familial prion diseases. Prion 7:4 1-11 Impact Factor 2.5

Trost, B., Arsenault, R., Griebel, P., Napper, S. and Kusalik, A. (2013) DAPPLE: a pipeline for the homology-based prediction of phosphorylation sites. Bioinformatics Epud ahead of print May 31 Impact Factor 5.5

 Arsenault, R. J., Napper, S. and Kogut, M. H. (2013) Salmonella enteric Typhimurium infection causes metabolic changes in chicken muscle involving AMPK, fatty acid and insulin/mTOR signaling. Vet. Res. 44:35 Impact Factor 3.6

Xu, X., Ball, L., Chen, W., Tian, X., Lambrecht, A., Hanna, M. and Xiao, W. (2013) The yeast Shu complex utilizes homologous recombination machinery for error-free lesion bypass via physical interaction with a Rad51 paralogue. PLoS One 8: e81371.

Tian, X., Xu, X. and Xiao, W. (2013) Novel method for genomic promoter shuffling using recyclable cassettes. Appl. Environ. Microbiol. 79: 7042-7047.

Qin, Z., Lu, M., Xu, X., Hanna, M., Shiomi, N. and Xiao, W. (2013) DNA-damage tolerance mediated by PCNA•Ub fusions in human cells is dependent on Rev1 but not Polh. Nucleic Acids Res. 41: 7356-7369.

Bhat, A., Andersen, P.L., Qin, Z. and Xiao, W. (2013) Rev3, the catalytic subunit of Polz, is required for maintaining fragile site stability in human cells. Nucleic Acids Res. 41: 2328-2339.

Wei, T., Zhang, C., Xu, X., Hanna, M., Zhang, X., Wang, Y., Dai, H. and Xiao, W. (2013) Construction and evaluation of two biosensors based on yeast transcriptional response to genotoxic chemicals. Biosensors and Bioelectronics. 44: 138-145.

Ross, Rebecca L., Julie E. Burns, Claire F. Taylor, Paul Mellor, Deborah H. Anderson and Margaret A. Knowles (2013) Identification of mutations in distinct regions of p85 alpha in urothelial cancer PLoS One, 8, e84411. 

Mellor, Paul, Leah Deibert, Brian Calvert, Keith Bonham, Svein A. Carlsen and Deborah H. Anderson (2013) CREB3L1 is a metastasis suppressor that represses expression of genes regulating metastasis, invasion and angiogenesis.  Mol Cell Biol, 33, 4985-4995.

van Straaten, K.E., Ko, J.K., Jagdhane, R., Anjum, S., Palmer, D.R.J., and Sanders, D.A.R.* (2013) The Structure of NtdA, a Sugar Aminotransferase Involved in the Kanosamine Biosynthetic Pathway in Bacillus subtilis, Reveals a New Sub-class of Aminotransferases. J. Biol. Chem., 288: 34121-34130

Dalrymple, S.A., Ko, J., Sheoran, I., Kaminskyj, S.G.W., and Sanders, D. A. R.* (2013) Elucidation of Substrate Specificity in Aspergillus nidulans UDP-Galactose-4-epimerase. PLoS One, 8: e76803.

Zheng, H., Bertwistle, D., Sanders, D. A. R. and Palmer, D. R. J.* (2013) Converting NAD-Specific Inositol Dehydrogenase to an Efficient NADP-Selective Catalyst, with a Surprising Twist. Biochemistry , 52: 5876-5883.

Vetter, N.D., Langill, D.M., Anjum, S., Boisvert-Martel, J., Jagdhane, R.C., Omene, E., Zheng, H., van Straaten, K.E., Asiamah, I., Krol, E.S., Sanders, D.A.R. and Palmer, D.R.J.* (2013) A Previously-Unrecognized Kanosamine Biosynthesis Pathway in Bacillus subtilis. J. Amer. Chem. Soc., 135: 5970-5973.

Olesya A. Kharenko; Devin Polichuk; Ken M. Nelson; Suzanne R. Abrams; Michele C. Loewen (2013) Identification and characterization of interactions between abscisic acid and human heat shock protein 70 family members J Biochem 154:383-391 [PDF]

Olesya A. Kharenko, Pooja Choudhary, Michele C. Loewen (2013) Abscisic acid binds to recombinant Arabidopsis thaliana G-protein coupled receptor-type G-protein 1 in Sacaromycese cerevisiae and in vitro. Plant Physiol Biochem 68:32-6. [PDF]

Lyudmyla Dorosh, Olesya A. Kharenko, Nandahkishore Rajagopalan, Michele C. Loewen, Maria Stepanova (2013) Molecular mechanisms in the activation of abscisic acid receptor PYR1. PLoS Comput Biol 9(6):e1003114. [PDF]

Peter C. Loewen, Allison L. Didychuk, Jacek Switala, Rosa Perez-Luque, Ignatio Fita, Michele C. Loewen (2013) Structure of Pisum Sativum RUbisco with bound ribulose 1,5-bisphosphate Acta Crystallographica F 69:10-14. [PDF]

Ahuja, G., Jaiswal, S., Hucl., P. and Chibbar, R.N. (2013) Genome specific granule-bound starch synthase I (GBSSI) influences starch biochemical and functional characteristics in near-isogenic wheat (Triticum aestivum L.) lines.  J. Agric. Food Chem. 61: 12129-12138. 

Mir T, Huang SH, Kobryn K. The telomere resolvase of the Lyme disease spirochete, Borrelia burgdorferi, promotes DNA single-strand annealing and strand exchange. Nucl. Acids Res. 2013 41 (22): 10438-10448. doi:10.1093/nar/gkt832