2017 PRISM Publications

Jakova, E. and Lee, J.S. (2017) Behaviour of a-synuclein-drug complexes during nano pore analysis with a superimposed AC field. Electrophoresis. 38(2):350-360.

Ara, A., Love, R.P., Follack, T.B., Ahmed, K.A., Adolph, M.B., Chelico, L. (2017) Mechanism of Enhanced HIV Restriction by Virion Coencapsidated Cytidine Deaminases APOBEC3F and APOBEC3G. Jurnal of Virology. 91: e02230-16.

Adolph, M.B., Ara, A., Feng, Y., Wittkopp, C.J., Emerman, M., Fraser, J.S., Chelico, L. (2017) Cytidine deaminase efficiency of the lentiviral viral restriction factor APOBEC3C correlates with dimerization. Nucleic Acids Research. 45(6):3378-3394.

Wong, K., Perpich, J.D., Kozlov, G., Cygler, M., Abu Kwaik, Y., Gehring, K. (2017) Structural Mimicry by a Bacterial F Box Effector Hijacks the Host Ubiquitin-Proteasome System. Structure. 2017 Feb 7;25(2):376-383.

Ulaganathan, T., Shi, R., Yao, D., Gu, R.X., Garron, M.L., Cherney, M., Tieleman, D.P., Sterner, E., Li, G., Li, L., Linhardt, R.J., Cygler, M. (2017) Conformational flexibility of PL12 family heparinases: structure and substrate specificity of heparinase III from Bacteroides thetaiotaomicron (BT4657). Glycobiology. 2017 Jan;27(2):176-187.

Huang, S.H., Cozart, M.R., Hart, M.A., Kobryn, K. (2017) The Borrelia burgdorferi telomere resolvase, ResT, possesses ATP-dependent DNA unwinding activity. Nucleic Acids Res.  45(3):1319-1329.

Jaiswal, S. and Chibbar, R.N. (2017) Amylopectin small chain glucans form structure fingerprint that determines botanical origin of starch.  Carbohydrate Polymers 158:112-123.

Raja, R.B., Agasimani, S., Jaiswal, S., Thiruvengadam, V., Sabariappan, R., Chibbar, R.N. and Ganseh Eam, S. (2017) EcoTILLING by sequencing reveals polymorphisms in genes encoding starch synthases that are associated with low glycemic response in rice.  BMC Plant Biology 17:13

Li, G.. and Howard, S.P. (2017) In vivo and in vitro protein-peptidoglycan interactions. Cascale E., Journet L.  Bacterial Protein Secretion Systems: Methods and Protocols. : 1-14. Springer New York.  in press.

Vanderlinde, E.M., Strozen, T.G., Hernandez, S.B., Cava, F., and Howard, S.P., (2017) Alterations in peptidoglycan cross-linking suppress the secretin assembly defect caused by mutation of GspA in the type II secretion system.  J. Bacteriol. doi: 10.1128/JB.00617-16 Posted online Jan 30 2017.

Alcorn, J., Whiting, S.J., Viveky, N., Di, Y.,  Mansell, K., Fowler, S., Thorpe, L., Almousa, A., Cheng, P.C., Jones, J., Billinsky, J., Hadjistavropoulos, T.J. (2017) Protocol for a 24-Week Randomized Controlled Study of Once-Daily Oral Dose of Flax Lignan to Healthy Older Adults. JMIR Research Protocols 6 (2), e14.

Hubick, S., Jayaraman, A., McKeen, A., Reid, S., Alcorn, J., Stavrindes, J., Sterenberg, B.T. (2017) A potent synthetic inorganic antibiotic with activity against drug-resistant pathogens. Scientific Reports 7, 41999.

Yu, C.H., Dolgova, N.V., and Dmitriev, O.Y. (2017) Dynamics of the metal binding domains and regulation of the human copper transporters ATP7B and ATP7A. IUBMB Life, Epub ahead of print, March 8, 2017.

Ulaganathan, T., Boniecki, M.T., Foran, E., Buravenkov, V., Mizrachi, N., Banin, E., Helbert, W., Cygler, M. (2017) New ulvan-degrading polysaccharide lyase family: structure and catalytic mechanism suggests convergent evolution of active site architecture. ACS Chem Biol. Mar 14. doi: 10.1021/acschembio.7b00126. [Epub ahead of print].

Huang, SH, Hart M.A., Wade M, Cozart M.R., McGrath S.L., Kobryn K. Biochemical characterization of Borrelia burgdorferi's RecA protein. PLoS One. 2017 Oct 31;12(10):e0187382. doi: 10.1371/journal.pone.0187382.

Whitecross, D.E., and Anderson, D.H. (2017) Identification of the binding sites on Rab5 and p110beta phosphatidylinositol 3-kinase. Sci Rep. 2017; 7: 16194

Smith, S.E., Mellor, P., Ward, A.K., Kendall, S., McDonald, M., Vizeacoumar, F.S., Vizeacoumar, F.J., Napper, S. and Anderson, D.H. (2017) Intrinsic pathway activation in a large panel of breast cancer cell lines. Breast Cancer Res,19(1):65.

Wu, Q., Li, Z., Mellor, P., Zhou, Y., Anderson, D.H. and Liu, Q. (2017) The role of PTEN – HCV core interaction in hepatitis C virus replication.  Sci Rep. 7(1):3695.

Morse, M., Huo, R., Feng, Y., Rouzina, I. and Chelico, L. and Williams, M.C. (2017) Dimerization regulates both deaminase-dependent and deaminase-independent HIV-1 restriction by APOBEC3G. Nature Communications, 8(1):597.

Adolph, M.B., Love, R.P., Feng, Y. and Chelico, L. (2017) Enzyme cycling contributes to efficient induction of genome mutagenesis by the cytidine deaminase APOBEC3B. Nucleic Acids Research, 45, 11925-11940.

Feng, Y., Goubran, M.H., Follack, T.B. and Chelico, L. (2017) Deamination-independent restriction of LINE-1 retrotransposition by APOBEC3H. Scientific Reports, 7(1):10881.

Davies, G., Lobanova, L., Dawicki, W., Groot, G., Gordon, J.R., Bowen, M., Harkness, T. and Arnason, T. (2017) Metformin inhibits the development, and promotes the resensitization, of treatment-resistant breast cancer. PLoS One, 12(12):e0187191.

Baxi, K., Ghavidel, A., Waddell, B., Harkness, T.A. and de Carvalho, C.E. (2017) Regulation of Lysosomal Function by the DAF-16 Forkhead Transcription Factor Couples Reproduction to Aging in Caenorhabditis elegans. Genetics, 207(1):83-101.

Vidhyasagar, V., He, Y., Guo, M., Talwar, T., Singh, R.S., Yadav, M., Katselis, G., Vizeacoumar, F.J., Lukong, K.E. and Wu, Y. (2017) Biochemical characterization of INTS3 and C9ORF80, two subunits of hNABP1/2 heterotrimeric complex in nucleic acid binding. Biochem J. 475(1):45-60.

Talwar, T., Vidhyasagar, V., Qing, J., Guo, M., Kariem, A., Lu, Y., Singh,R.S., Lukong, K.E. and Wu, Y. (2017) The DEAD-box Protein DDX43 (HAGE) Is a Dual RNA-DNA Helicase and Has a K-homology Domain Required for Full Nucleic Acid Unwinding Activity. J Biol Chem. 292:10429-10443.

Grochulski, P., Fodje, M., Labiuk, S., Wysokinski, T.W., Belev, G., Korbas, M., Rosendahl, S.M. (2017) Review of Canadian Light Source facilities for biological applications. Nuclear Instruments and Methods in Physics Research Section B, Beam Interactions with Materials and Atoms. 411, 17-21.

Kgosisejo, O., Chen, J.A., Grochulski, P., Tanaka, T. (2017). Crystallographic structure of recombinant Lactococcus lactis prolidase to support proposed structure-function relationships. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1865(5) ,473-480.

Vetter, N.D. and Palmer, D.R.J. (2017) Simultaneous measurement of glucose-6-phosphate 3-dehydrogenase (NtdC) catalysis and the nonenzymatic reaction of its product: kinetics and isotope effects on the first step in kanosamine biosynthesis. Biochemistry, 56, 2001-2009.

Alharbi, H.A., Alcorn, J., Al-Mousa, A., Giesy, J.P., Wiseman, S.B. (2017) Toxicokinetics and toxicodynamics of chlorpyrifos is altered in embryos of Japanese medaka exposed to oil sands process-affected water: evidence for inhibition of P-glycoprotein. J Appl Toxicol., 37(5):591-601.

Di, Y.., Ji, S., Wolf, P., Krol, E.S. and Alcorn, J. (2017) Enterolactone glucuronide and β-glucuronidase in antibody directed enzyme prodrug therapy for targeted prostate cancer cell treatment. AAPS PharmSciTech., 18(6):2336-2345.

Johnston, C.A., Dickinson, V.S.M., Alcorn, J. and Gaunt, M.C. (2017) Pharmacokinetics and oral bioavailability of metformin hydrochloride in healthy mixed-breed dogs. Am J Vet Res., 78(10):1193-1199.

Di, Y., Jones, J., Mansell, K., Whiting, S., Fowler, S., Thorpe, L., Billinsky, J., Viveky, N., Cheng, P.C., Almousa, A., Hadjistavropoulos, T., Alcorn, J. (2017) Influence of Flaxseed Lignan Supplementation to Older Adults on Biochemical and Functional Outcome Measures of Inflammation. J Am Coll Nutr., 36(8):646-653.

Zhang, W., Zhuang, Y., Zhang, Y., Yang, X., Zhang, H., Wang, G., Yin, W., Wang, R., Zhang, Z. and Xiao, W. (2017) Uev1A facilitates osteosarcoma differentiation by promoting Smurf1-mediated Smad1 ubiquitination and degradation. Cell Death & Disease 8: e2974.

Wang, Q., Zang, Y., Zhou, X. and Xiao, W. (2017) Characterization of four rice UEV1 genes required for Lys63-linked polyubiquitination and distinct functions. BMC Pl. Biol. 17: 126.

Bhat, A., Qin, Z., Wang, G., Chen, W. and Xiao, W. (2017) Rev7, the regulatory subunit of Polζ, undergoes UV-induced and Cul4-dependent degradation. FEBS J. 284: 1790-1803. (Cover and Editor’s Choice for issue 12, and is included in a special annual highlights virtual issue).

Wang, Q., Xue, H., Li, S., Chen, Y., Tian, X., Xu, X., Xiao, W. and Fu, Y. (2017) A method for labeling proteins with tags at the native genomic loci in budding yeast. PLoS One 12: e6176184.

Ulaganathan, T.S., Shi, R., Yao, D., Gu, R.X., Garron, M.L., Cherney, M., Tielman, D.P., Sterner, E., Li, G., Linhardt R.J. and Cygler, M. (2017) Conformational Flexibility of PL12 family Heparinases: Structure and Substrate Specificity of Heparinase III from Bacteroides thetaiotaomicron (BT4657). Glycobiology, 27(2):176-187.

Zhao, J., Beyrakhova, K., Liu, Y., Alvarez, C.P., Bueler, S.A., Xu, L., Xu, C., Boniecki, M.T., Kanelis, V., Luo, Z.-Q., Cygler, M. and Rubinstein, J.L. (2017). Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein. PLoS Pathogen, 13(6) e1006394.

Gagarinova, A., Phanse, S., Cygler, M. and Babu, M. (2017) Insights from protein-protein interaction studies on bacterial pathogenesis. Expert Rev. Proteomics, 14(9), 779-797.

Boniecki, M.T., Freibert, S.A., Mühlenhoff, U., Lill, R. and Cygler, M. (2017) Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex. Nat Commun. 8(1), 1287.

Dolgova, N.V., Yu, C.H., Cvitkovic, J.P., Hodak, M., Nienaber, K.H., Summers, K.L., Cotelesage, J.J.H., Bernholc, J., Kaminski, G.A., Pickering, I.J., George, G.N., Dmitriev, O.Y. (2017) Binding of Copper and Cisplatin to Atox1 Is Mediated by Glutathione through the Formation of Metal-Sulfur Clusters. Biochemistry, 56(24):3129-3141.

Yu, C.H., Yang, N., Bothe, J., Tonelli, M., Nokhrin, S., Dolgova, N.V., Braiterman, L., Lutsenko, S., Dmitriev, O.Y. (2017) The metal chaperone Atox1 regulates the activity of the human copper transporter ATP7B by modulating domain dynamics. J Biol Chem, 292(44):18169-18177.

Köster, W. (2017) Vaccinating poultry in the egg against Salmonella and Campylobacter bacteria. Agriview (Government of Saskatchewan) 13(5):11.

MacKenzie, K.D., Palmer, M.B., Köster, W.L. and White, A.P. (2017) Examining the Link between Biofilm Formation and the Ability of Pathogenic Salmonella strains to Colonize Multiple Host Species. Frontiers in Vet Sci. 4: 138.

Hu, Y., Huang, H., Cheng, X., Shu, X., White, A.P., Stavrinides, J., Köster, W., Zhu, G., Zhao, Z., Wang, Y. (2017) A global survey of bacterial type III secretion systems and their effectors. Environ. Microbiol. 19(10):3879-3895.